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Oncogenes: The Passport for Viral Oncolysis Through PKR Inhibition
The transforming properties of oncogenes are derived from gain-of-function mutations, shifting cell signaling from highly regulated homeostatic to an uncontrolled oncogenic state, with the contribution of the inactivating mutations in tumor suppressor genes P53 and RB, leading to tumor resistance to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Libertas Academica
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966488/ https://www.ncbi.nlm.nih.gov/pubmed/27486347 http://dx.doi.org/10.4137/BIC.S33378 |