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Connection between self-stigma, adherence to treatment, and discontinuation of medication

INTRODUCTION: Self-stigma plays a role in many areas of the patient’s life. Furthermore, it also discourages therapy. The aim of our study was to examine associations between self-stigma and adherence to treatment and discontinuation of medication in patients from various diagnostic groups. METHODS:...

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Autores principales: Kamaradova, Dana, Latalova, Klara, Prasko, Jan, Kubinek, Radim, Vrbova, Kristyna, Mainerova, Barbora, Cinculova, Andrea, Ociskova, Marie, Holubova, Michaela, Smoldasova, Jarmila, Tichackova, Anezka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966500/
https://www.ncbi.nlm.nih.gov/pubmed/27524884
http://dx.doi.org/10.2147/PPA.S99136
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author Kamaradova, Dana
Latalova, Klara
Prasko, Jan
Kubinek, Radim
Vrbova, Kristyna
Mainerova, Barbora
Cinculova, Andrea
Ociskova, Marie
Holubova, Michaela
Smoldasova, Jarmila
Tichackova, Anezka
author_facet Kamaradova, Dana
Latalova, Klara
Prasko, Jan
Kubinek, Radim
Vrbova, Kristyna
Mainerova, Barbora
Cinculova, Andrea
Ociskova, Marie
Holubova, Michaela
Smoldasova, Jarmila
Tichackova, Anezka
author_sort Kamaradova, Dana
collection PubMed
description INTRODUCTION: Self-stigma plays a role in many areas of the patient’s life. Furthermore, it also discourages therapy. The aim of our study was to examine associations between self-stigma and adherence to treatment and discontinuation of medication in patients from various diagnostic groups. METHODS: This cross-sectional study involved outpatients attending the Department of Psychiatry, University Hospital Olomouc, Czech Republic. The level of self-stigma was measured with the Internalized Stigma of Mental Illness and adherence with the Drug Attitude Inventory. The patients also anonymously filled out a demographic questionnaire which included a question asking whether they had discontinued their medication in the past. RESULTS: We examined data from 332 patients from six basic diagnostic categories (substance abuse disorders, schizophrenia, bipolar disorders, depressive disorders, anxiety disorders, and personality disorders). The study showed a statistically significant negative correlation between self-stigma and adherence to treatment in all diagnostic groups. Self-stigma correlated positively and adherence negatively with the severity of disorders. Another important factor affecting both variables was partnership. Self-stigma positively correlated with doses of antidepressants and adherence with doses of anxiolytics. Self-stigma also negatively correlated with education, and positively with a number of hospitalizations and number of psychiatrists visited. Adherence was further positively correlated with age and age of onset of disorders. Regression analysis showed that self-stigma was an important factor negatively influencing adherence to treatment and significantly contributing to voluntary discontinuation of drugs. The level of self-stigma did not differ between diagnostic categories. Patients suffering from schizophrenia had the lowest adherence to treatment. CONCLUSION: The study showed a significant correlation between self-stigma and adherence to treatment. High levels of self-stigma are associated with discontinuation of medications without a psychiatrist’s recommendation. This connection was present in all diagnostic groups.
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spelling pubmed-49665002016-08-12 Connection between self-stigma, adherence to treatment, and discontinuation of medication Kamaradova, Dana Latalova, Klara Prasko, Jan Kubinek, Radim Vrbova, Kristyna Mainerova, Barbora Cinculova, Andrea Ociskova, Marie Holubova, Michaela Smoldasova, Jarmila Tichackova, Anezka Patient Prefer Adherence Original Research INTRODUCTION: Self-stigma plays a role in many areas of the patient’s life. Furthermore, it also discourages therapy. The aim of our study was to examine associations between self-stigma and adherence to treatment and discontinuation of medication in patients from various diagnostic groups. METHODS: This cross-sectional study involved outpatients attending the Department of Psychiatry, University Hospital Olomouc, Czech Republic. The level of self-stigma was measured with the Internalized Stigma of Mental Illness and adherence with the Drug Attitude Inventory. The patients also anonymously filled out a demographic questionnaire which included a question asking whether they had discontinued their medication in the past. RESULTS: We examined data from 332 patients from six basic diagnostic categories (substance abuse disorders, schizophrenia, bipolar disorders, depressive disorders, anxiety disorders, and personality disorders). The study showed a statistically significant negative correlation between self-stigma and adherence to treatment in all diagnostic groups. Self-stigma correlated positively and adherence negatively with the severity of disorders. Another important factor affecting both variables was partnership. Self-stigma positively correlated with doses of antidepressants and adherence with doses of anxiolytics. Self-stigma also negatively correlated with education, and positively with a number of hospitalizations and number of psychiatrists visited. Adherence was further positively correlated with age and age of onset of disorders. Regression analysis showed that self-stigma was an important factor negatively influencing adherence to treatment and significantly contributing to voluntary discontinuation of drugs. The level of self-stigma did not differ between diagnostic categories. Patients suffering from schizophrenia had the lowest adherence to treatment. CONCLUSION: The study showed a significant correlation between self-stigma and adherence to treatment. High levels of self-stigma are associated with discontinuation of medications without a psychiatrist’s recommendation. This connection was present in all diagnostic groups. Dove Medical Press 2016-07-22 /pmc/articles/PMC4966500/ /pubmed/27524884 http://dx.doi.org/10.2147/PPA.S99136 Text en © 2016 Kamaradova et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Kamaradova, Dana
Latalova, Klara
Prasko, Jan
Kubinek, Radim
Vrbova, Kristyna
Mainerova, Barbora
Cinculova, Andrea
Ociskova, Marie
Holubova, Michaela
Smoldasova, Jarmila
Tichackova, Anezka
Connection between self-stigma, adherence to treatment, and discontinuation of medication
title Connection between self-stigma, adherence to treatment, and discontinuation of medication
title_full Connection between self-stigma, adherence to treatment, and discontinuation of medication
title_fullStr Connection between self-stigma, adherence to treatment, and discontinuation of medication
title_full_unstemmed Connection between self-stigma, adherence to treatment, and discontinuation of medication
title_short Connection between self-stigma, adherence to treatment, and discontinuation of medication
title_sort connection between self-stigma, adherence to treatment, and discontinuation of medication
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966500/
https://www.ncbi.nlm.nih.gov/pubmed/27524884
http://dx.doi.org/10.2147/PPA.S99136
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