Key factors influencing ADME properties of therapeutic proteins: A need for ADME characterization in drug discovery and development

Protein therapeutics represent a diverse array of biologics including antibodies, fusion proteins, and therapeutic replacement enzymes. Since their inception, they have revolutionized the treatment of a wide range of diseases including respiratory, vascular, autoimmune, inflammatory, infectious, and...

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Detalles Bibliográficos
Autores principales: Tibbitts, Jay, Canter, David, Graff, Ryan, Smith, Alison, Khawli, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966629/
https://www.ncbi.nlm.nih.gov/pubmed/26636901
http://dx.doi.org/10.1080/19420862.2015.1115937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966629/
https://www.ncbi.nlm.nih.gov/pubmed/26636901
http://dx.doi.org/10.1080/19420862.2015.1115937

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