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Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms

The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to generate them for therapeutic use in many disease areas. Historically, the discovery of therapeutic mAbs has relied upon the immunization of mammals and various in vitro dis...

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Detalles Bibliográficos
Autores principales: Abdiche, Yasmina Noubia, Harriman, Rian, Deng, Xiaodi, Yeung, Yik Andy, Miles, Adam, Morishige, Winse, Boustany, Leila, Zhu, Lei, Izquierdo, Shelley Mettler, Harriman, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966639/
https://www.ncbi.nlm.nih.gov/pubmed/26652308
http://dx.doi.org/10.1080/19420862.2015.1118596