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Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms
The ability of monoclonal antibodies (mAbs) to target specific antigens with high precision has led to an increasing demand to generate them for therapeutic use in many disease areas. Historically, the discovery of therapeutic mAbs has relied upon the immunization of mammals and various in vitro dis...
Autores principales: | Abdiche, Yasmina Noubia, Harriman, Rian, Deng, Xiaodi, Yeung, Yik Andy, Miles, Adam, Morishige, Winse, Boustany, Leila, Zhu, Lei, Izquierdo, Shelley Mettler, Harriman, William |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966639/ https://www.ncbi.nlm.nih.gov/pubmed/26652308 http://dx.doi.org/10.1080/19420862.2015.1118596 |
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