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Efficacy of ultra-micronized palmitoylethanolamide (um-PEA) in geriatric patients with chronic pain: study protocol for a series of N-of-1 randomized trials
BACKGROUND: Chronic pain in older people is highly prevalent, often underestimated, and associated with adverse outcomes. Most available analgesic drugs are often either ineffective or not tolerated, with many side effects. Palmitoylethanolamide (PEA) is an endogenous widely distributed N-acylethano...
Autores principales: | Marcucci, Maura, Germini, Federico, Coerezza, Anna, Andreinetti, Luca, Bellintani, Lorenzo, Nobili, Alessandro, Rossi, Paolo Dionigi, Mari, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966710/ https://www.ncbi.nlm.nih.gov/pubmed/27473188 http://dx.doi.org/10.1186/s13063-016-1496-9 |
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