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MicroRNA 433 regulates nonsense-mediated mRNA decay by targeting SMG5 mRNA

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a RNA quality surveillance system for eukaryotes. It prevents cells from generating deleterious truncated proteins by degrading abnormal mRNAs that harbor premature termination codon (PTC). However, little is known about the molecular regulation mech...

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Detalles Bibliográficos
Autores principales:	Jin, Yi, Zhang, Fang, Ma, Zhenfa, Ren, Zhuqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966760/ https://www.ncbi.nlm.nih.gov/pubmed/27473591 http://dx.doi.org/10.1186/s12867-016-0070-z

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