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β-arrestin1 at the cross-road of endothelin-1 signaling in cancer
The advent of targeted therapeutics in human cancer has begun to find novel druggable targets and, in this context, the endothelin-1 receptor (ET-1R), namely ET(A) receptor (ET(A)R) and ET(B) receptor, among the GPCR family represents a class of highly druggable molecules in cancer. ET-1R are aberra...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966762/ https://www.ncbi.nlm.nih.gov/pubmed/27473335 http://dx.doi.org/10.1186/s13046-016-0401-4 |