How do researchers determine the difference to be detected in superiority trials? Results of a survey from a panel of researchers

BACKGROUND: There is currently no guidance for selecting a specific difference to be detected in a superiority trial. We explored 3 factors that in our opinion should influence the difference to be detected (type of outcome, patient age group, and presence of treatment side-effects), and 3 that shou...

Descripción completa

Detalles Bibliográficos
Autores principales: Gayet-Ageron, Angèle, Jannot, Anne-Sophie, Agoritsas, Thomas, Rudaz, Sandrine, Combescure, Christophe, Perneger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966776/
https://www.ncbi.nlm.nih.gov/pubmed/27473336
http://dx.doi.org/10.1186/s12874-016-0195-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966776/
https://www.ncbi.nlm.nih.gov/pubmed/27473336
http://dx.doi.org/10.1186/s12874-016-0195-2

Ejemplares similares