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Telomere length shortening is associated with treatment-free remission in chronic myeloid leukemia patients
We studied telomere length in 32 CML patients who discontinued imatinib after achieving complete molecular remission and 32 age-sex-matched controls. The relative telomere length (RTL) was determined by q-PCR as the telomere to single copy gene (36B4) ratio normalized to a reference sample (K-562 DN...
Autores principales: | Caocci, Giovanni, Greco, Marianna, Delogu, Giuseppe, Secchi, Christian, Martino, Bruno, Labate, Claudia, Abruzzese, Elisabetta, Trawinska, Malgorzata Monika, Galimberti, Sara, Orru, Federica, Fozza, Claudio, Passerini, Carlo Gambacorti, Galimi, Francesco, La Nasa, Giorgio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966800/ https://www.ncbi.nlm.nih.gov/pubmed/27473052 http://dx.doi.org/10.1186/s13045-016-0293-y |
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