Proteinase-activated receptor 2 (PAR(2)) in hepatic stellate cells – evidence for a role in hepatocellular carcinoma growth in vivo

BACKGROUND: Previous studies have established that proteinase-activated receptor 2 (PAR(2)) promotes migration and invasion of hepatocellular carcinoma (HCC) cells, suggesting a role in HCC progression. Here, we assessed the impact of PAR(2) in HCC stromal cells on HCC growth using LX-2 hepatic stel...

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Detalles Bibliográficos
Autores principales: Mußbach, Franziska, Ungefroren, Hendrik, Günther, Bernd, Katenkamp, Kathrin, Henklein, Petra, Westermann, Martin, Settmacher, Utz, Lenk, Lennart, Sebens, Susanne, Müller, Jörg P., Böhmer, Frank-Dietmar, Kaufmann, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966804/
https://www.ncbi.nlm.nih.gov/pubmed/27473374
http://dx.doi.org/10.1186/s12943-016-0538-y

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