A novel rodent Chapparvovirus in feces of wild rats

Chapparvovirus, a recently determined new genus in the family Parvoviridae, can infect many species of animals including bats, chickens, and pigs. Here, using viral metagenomics method, we identified a novel Chapparvovirus from feces of wild rats and designated it as rat parvovirus 2 (RPV2). The nea...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Shixing, Liu, Zhijian, Wang, Yan, Li, Wang, Fu, Xingli, Lin, Yuan, Shen, Quan, Wang, Xiaochun, Wang, Hua, Zhang, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966819/
https://www.ncbi.nlm.nih.gov/pubmed/27473724
http://dx.doi.org/10.1186/s12985-016-0589-0
_version_ 1782445441097400320
author Yang, Shixing
Liu, Zhijian
Wang, Yan
Li, Wang
Fu, Xingli
Lin, Yuan
Shen, Quan
Wang, Xiaochun
Wang, Hua
Zhang, Wen
author_facet Yang, Shixing
Liu, Zhijian
Wang, Yan
Li, Wang
Fu, Xingli
Lin, Yuan
Shen, Quan
Wang, Xiaochun
Wang, Hua
Zhang, Wen
author_sort Yang, Shixing
collection PubMed
description Chapparvovirus, a recently determined new genus in the family Parvoviridae, can infect many species of animals including bats, chickens, and pigs. Here, using viral metagenomics method, we identified a novel Chapparvovirus from feces of wild rats and designated it as rat parvovirus 2 (RPV2). The nearly complete genome of RPV2 is 4222-nt long and includes two ORFs encoding a 654-aa nonstructural protein 1 (NS1) and a 472-aa capsid protein (VP), respectively. Phylogenetic analysis over the amino acid sequence of the NS1 showed that RPV2 clustered with Eidolon helvum parvovirus 2 (EHPV2), porcine parvovirus 7 (PPV7), and turkey parvovirus 1 (TP1), forming a separate clade. Sequence analysis indicated that the NS1 protein of RPV2 shared the highest amino acid sequence identity (51 %) with that of EHPV2. According to the genetic distance-based criteria, RPV2 identified here belongs to a novel species of Chapparvovirus.
format Online
Article
Text
id pubmed-4966819
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-49668192016-07-30 A novel rodent Chapparvovirus in feces of wild rats Yang, Shixing Liu, Zhijian Wang, Yan Li, Wang Fu, Xingli Lin, Yuan Shen, Quan Wang, Xiaochun Wang, Hua Zhang, Wen Virol J Short Report Chapparvovirus, a recently determined new genus in the family Parvoviridae, can infect many species of animals including bats, chickens, and pigs. Here, using viral metagenomics method, we identified a novel Chapparvovirus from feces of wild rats and designated it as rat parvovirus 2 (RPV2). The nearly complete genome of RPV2 is 4222-nt long and includes two ORFs encoding a 654-aa nonstructural protein 1 (NS1) and a 472-aa capsid protein (VP), respectively. Phylogenetic analysis over the amino acid sequence of the NS1 showed that RPV2 clustered with Eidolon helvum parvovirus 2 (EHPV2), porcine parvovirus 7 (PPV7), and turkey parvovirus 1 (TP1), forming a separate clade. Sequence analysis indicated that the NS1 protein of RPV2 shared the highest amino acid sequence identity (51 %) with that of EHPV2. According to the genetic distance-based criteria, RPV2 identified here belongs to a novel species of Chapparvovirus. BioMed Central 2016-07-29 /pmc/articles/PMC4966819/ /pubmed/27473724 http://dx.doi.org/10.1186/s12985-016-0589-0 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Yang, Shixing
Liu, Zhijian
Wang, Yan
Li, Wang
Fu, Xingli
Lin, Yuan
Shen, Quan
Wang, Xiaochun
Wang, Hua
Zhang, Wen
A novel rodent Chapparvovirus in feces of wild rats
title A novel rodent Chapparvovirus in feces of wild rats
title_full A novel rodent Chapparvovirus in feces of wild rats
title_fullStr A novel rodent Chapparvovirus in feces of wild rats
title_full_unstemmed A novel rodent Chapparvovirus in feces of wild rats
title_short A novel rodent Chapparvovirus in feces of wild rats
title_sort novel rodent chapparvovirus in feces of wild rats
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966819/
https://www.ncbi.nlm.nih.gov/pubmed/27473724
http://dx.doi.org/10.1186/s12985-016-0589-0
work_keys_str_mv AT yangshixing anovelrodentchapparvovirusinfecesofwildrats
AT liuzhijian anovelrodentchapparvovirusinfecesofwildrats
AT wangyan anovelrodentchapparvovirusinfecesofwildrats
AT liwang anovelrodentchapparvovirusinfecesofwildrats
AT fuxingli anovelrodentchapparvovirusinfecesofwildrats
AT linyuan anovelrodentchapparvovirusinfecesofwildrats
AT shenquan anovelrodentchapparvovirusinfecesofwildrats
AT wangxiaochun anovelrodentchapparvovirusinfecesofwildrats
AT wanghua anovelrodentchapparvovirusinfecesofwildrats
AT zhangwen anovelrodentchapparvovirusinfecesofwildrats
AT yangshixing novelrodentchapparvovirusinfecesofwildrats
AT liuzhijian novelrodentchapparvovirusinfecesofwildrats
AT wangyan novelrodentchapparvovirusinfecesofwildrats
AT liwang novelrodentchapparvovirusinfecesofwildrats
AT fuxingli novelrodentchapparvovirusinfecesofwildrats
AT linyuan novelrodentchapparvovirusinfecesofwildrats
AT shenquan novelrodentchapparvovirusinfecesofwildrats
AT wangxiaochun novelrodentchapparvovirusinfecesofwildrats
AT wanghua novelrodentchapparvovirusinfecesofwildrats
AT zhangwen novelrodentchapparvovirusinfecesofwildrats

Ejemplares similares