Cargando…

Clausenidin induces caspase-dependent apoptosis in colon cancer

BACKGROUND: Clausena excavata Burm.f. is a shrub traditionally used to treat cancer patients in Asia. The main bioactive chemical components of the plant are alkaloids and coumarins. In this study, we isolated clausenidin from the roots of C. excavata to determine its apoptotic effect on the colon c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Waziri, Peter M., Abdullah, Rasedee, Yeap, Swee Keong, Omar, Abdul Rahman, Kassim, Nur Kartinee, Malami, Ibrahim, How, Chee Wun, Etti, Imaobong Christopher, Abu, Mary Ladidi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966865/ https://www.ncbi.nlm.nih.gov/pubmed/27473055 http://dx.doi.org/10.1186/s12906-016-1247-1

Ejemplares similares

Clausenidin Induces Caspase 8-Dependent Apoptosis and Suppresses Production of VEGF in Liver Cancer Cells
por: Waziri, Peter M, et al.
Publicado: (2018)

Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells
por: Malami, Ibrahim, et al.
Publicado: (2017)

Correction: Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells
por: Malami, Ibrahim, et al.
Publicado: (2017)

In Silico Discovery of Potential Uridine-Cytidine Kinase 2 Inhibitors from the Rhizome of Alpinia mutica
por: Malami, Ibrahim, et al.
Publicado: (2016)

Artonin E and Structural Analogs from Artocarpus Species Abrogates Estrogen Receptor Signaling in Breast Cancer
por: Etti, Imaobong, et al.
Publicado: (2016)

Artonin E induces p53-independent G1 cell cycle arrest and apoptosis through ROS-mediated mitochondrial pathway and livin suppression in MCF-7 cells
por: Etti, Imaobong Christopher, et al.
Publicado: (2017)

The molecular mechanism of the anticancer effect of Artonin E in MDA-MB 231 triple negative breast cancer cells
por: Etti, Imaobong Christopher, et al.
Publicado: (2017)

An in silico approach in predicting the possible mechanism involving restoration of wild-type p53 functions by small molecular weight compounds in tumor cells expressing R273H mutant p53
por: Malami, Ibrahim, et al.
Publicado: (2017)

Characterization and toxicity of citral incorporated with nanostructured lipid carrier
por: Nordin, Noraini, et al.
Publicado: (2018)

In vitro cytotoxicity and anticancer effects of citral nanostructured lipid carrier on MDA MBA-231 human breast cancer cells
por: Nordin, Noraini, et al.
Publicado: (2019)

Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials
por: Rahman, Heshu Sulaiman, et al.
Publicado: (2014)

Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect
por: Rahman, Heshu Sulaiman, et al.
Publicado: (2013)

Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
por: Rahman, Heshu Sulaiman, et al.
Publicado: (2014)

Inclusion complex of clausenidin with hydroxypropyl-β-cyclodextrin: Improved physicochemical properties and anti-colon cancer activity
por: Al-Abboodi, Ashwaq Shakir, et al.
Publicado: (2021)

Acute Toxicity Study of Zerumbone-Loaded Nanostructured Lipid Carrier on BALB/c Mice Model
por: Rahman, Heshu Sulaiman, et al.
Publicado: (2014)

Recombinant Human erythropoietin reduces viability of MCF-7 breast cancer cells from 3D culture without caspase activation
por: ShujaaEdin, Hareth Y., et al.
Publicado: (2021)

Antitumor and Anti-Metastatic Effects of Citral-Loaded Nanostructured Lipid Carrier in 4T1-Induced Breast Cancer Mouse Model
por: Nordin, Noraini, et al.
Publicado: (2020)

Water extract of brewers’ rice induces apoptosis in human colorectal cancer cells via activation of caspase-3 and caspase-8 and downregulates the Wnt/β-catenin downstream signaling pathway in brewers’ rice-treated rats with azoxymethane-induced colon carcinogenesis
por: Tan, Bee Ling, et al.
Publicado: (2015)

Induction of cell cycle arrest and apoptosis in caspase-3 deficient MCF-7 cells by Dillenia suffruticosa root extract via multiple signalling pathways
por: Foo, Jhi Biau, et al.
Publicado: (2014)

Induction of Apoptosis in MCF-7 Cells via Oxidative Stress Generation, Mitochondria-Dependent and Caspase-Independent Pathway by Ethyl Acetate Extract of Dillenia suffruticosa and Its Chemical Profile
por: Tor, Yin Sim, et al.
Publicado: (2015)

Antileukemic effect of zerumbone-loaded nanostructured lipid carrier in WEHI-3B cell-induced murine leukemia model
por: Rahman, Heshu Sulaiman, et al.
Publicado: (2015)

Enhanced anti-mammary gland cancer activities of tamoxifen-loaded erythropoietin-coated drug delivery system
por: Beh, Chaw Yee, et al.
Publicado: (2019)

Cytotoxicity and Apoptosis Effects of Curcumin Analogue (2E,6E)-2,6-Bis(2,3-Dimethoxybenzylidine) Cyclohexanone (DMCH) on Human Colon Cancer Cells HT29 and SW620 In Vitro
por: Rahim, Nurul Fattin Che, et al.
Publicado: (2021)

Inducing G2/M Cell Cycle Arrest and Apoptosis through Generation Reactive Oxygen Species (ROS)-Mediated Mitochondria Pathway in HT-29 Cells by Dentatin (DEN) and Dentatin Incorporated in Hydroxypropyl-β-Cyclodextrin (DEN-HPβCD)
por: Ashwaq, Al-Abboodi Shakir, et al.
Publicado: (2016)

The flavokawains: uprising medicinal chalcones
por: Abu, Nadiah, et al.
Publicado: (2013)

Development of erythropoietin receptor-targeted drug delivery system against breast cancer using tamoxifen-loaded nanostructured lipid carriers
por: Beh, Chaw Yee, et al.
Publicado: (2017)

Application of PCR-ELISA in Molecular Diagnosis
por: Sue, Mei Jean, et al.
Publicado: (2014)

Advances in the study of nodavirus
por: Yong, Chean Yeah, et al.
Publicado: (2017)

Preparation and Characterization of Self Nano-Emulsifying Drug Delivery System Loaded with Citraland Its Antiproliferative Effect on Colorectal Cells In Vitro
por: Mohd Izham, Mira Nadiah, et al.
Publicado: (2019)

Zerumbone Suppresses Angiogenesis in HepG2 Cells through Inhibition of Matrix Metalloproteinase-9, Vascular Endothelial Growth Factor, and Vascular Endothelial Growth Factor Receptor Expressions
por: Samad, Nozlena Abdul, et al.
Publicado: (2017)

Zerumbone-Loaded Nanostructured Lipid Carrier Induces Apoptosis of Canine Mammary Adenocarcinoma Cells
por: Foong, Jia Ning, et al.
Publicado: (2018)

Innovative Method for Longer Effective Corrosion Inhibition Time: Controlled Release Oil Palm Empty Fruit Bunch Hemicellulose Inhibitor Tablet
por: Haris, Nur Izzah Nabilah, et al.
Publicado: (2021)

Novel Gold Nanoparticles Reduced by Sargassum glaucescens: Preparation, Characterization and Anticancer Activity
por: Ajdari, Zahra, et al.
Publicado: (2016)

Recombinant human Erythropoietin enhanced the cytotoxic effects of tamoxifen toward the spheroid MCF-7 breast cancer cells
por: Shujaa Edin, Hareth Y., et al.
Publicado: (2021)

Thymoquinone-Loaded Nanostructured Lipid Carrier Exhibited Cytotoxicity towards Breast Cancer Cell Lines (MDA-MB-231 and MCF-7) and Cervical Cancer Cell Lines (HeLa and SiHa)
por: Ng, Wei Keat, et al.
Publicado: (2015)

Potential recombinant vaccine against influenza A virus based on M2e displayed on nodaviral capsid nanoparticles
por: Yong, Chean Yeah, et al.
Publicado: (2015)

In Vitro Evaluation of Curcumin-Encapsulated Chitosan Nanoparticles against Feline Infectious Peritonitis Virus and Pharmacokinetics Study in Cats
por: Ng, Shing Wei, et al.
Publicado: (2020)

Bromelain Enhances the Anti-tumor Effects of Cisplatin on 4T1 Breast Tumor Model In Vivo
por: Mohamad, Nurul Elyani, et al.
Publicado: (2019)

Physicochemical characterization, cytotoxic effect and toxicity evaluation of nanostructured lipid carrier loaded with eucalyptol
por: Izham, Mira Nadiah Mohd, et al.
Publicado: (2021)

Immunomodulatory effects of Potentilla indica and Dendrophthoe pentandra on mice splenocytes and thymocytes
por: ANG, HUI YING, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_s9dks8g0bkg0c7pqf6clig0bcb