Towards onset prevention of cognition decline in adults with Down syndrome (The TOP-COG study): A pilot randomised controlled trial

BACKGROUND: Dementia is very common in Down syndrome (trisomy 21) adults. Statins may slow brain amyloid β (Aβ, coded on chromosome 21) deposition and, therefore, delay Alzheimer disease onset. One prospective cohort study with Down syndrome adults found participants on statins had reduced risk of i...

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Detalles Bibliográficos
Autores principales: Cooper, Sally-Ann, Ademola, Temitope, Caslake, Muriel, Douglas, Elizabeth, Evans, Jonathan, Greenlaw, Nicola, Haig, Caroline, Hassiotis, Angela, Jahoda, Andrew, McConnachie, Alex, Morrison, Jill, Ring, Howard, Starr, John, Stiles, Ciara, Sirisena, Chammy, Sullivan, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966871/
https://www.ncbi.nlm.nih.gov/pubmed/27473843
http://dx.doi.org/10.1186/s13063-016-1370-9

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