Intra-patient Inter-metastatic Genetic Heterogeneity in Colorectal Cancer as a Key Determinant of Survival after Curative Liver Resection

Chromosomal instability is a well-defined hallmark of tumor aggressiveness and metastatic progression in colorectal cancer. The magnitude of genetic heterogeneity among distinct liver metastases from the same patient at the copy number level, as well as its relationship with chemotherapy exposure an...

Descripción completa

Detalles Bibliográficos
Autores principales: Sveen, Anita, Løes, Inger Marie, Alagaratnam, Sharmini, Nilsen, Gro, Høland, Maren, Lingjærde, Ole Christian, Sorbye, Halfdan, Berg, Kaja Christine Graue, Horn, Arild, Angelsen, Jon-Helge, Knappskog, Stian, Lønning, Per Eystein, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966938/
https://www.ncbi.nlm.nih.gov/pubmed/27472274
http://dx.doi.org/10.1371/journal.pgen.1006225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966938/
https://www.ncbi.nlm.nih.gov/pubmed/27472274
http://dx.doi.org/10.1371/journal.pgen.1006225

Ejemplares similares