Cargando…

DNA Damage Responses Are Induced by tRNA Anticodon Nucleases and Hygromycin B

Previous studies revealed DNA damage to occur during the toxic action of PaT, a fungal anticodon ribonuclease (ACNase) targeting the translation machinery via tRNA cleavage. Here, we demonstrate that other translational stressors induce DNA damage-like responses in yeast as well: not only zymocin, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wemhoff, Sabrina, Klassen, Roland, Beetz, Anja, Meinhardt, Friedhelm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966947/
https://www.ncbi.nlm.nih.gov/pubmed/27472060
http://dx.doi.org/10.1371/journal.pone.0157611