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Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound

RNA interference has potential therapeutic value for cardiac disease, but targeted delivery of interfering RNA is a challenge. Custom designed microbubbles, in conjunction with ultrasound, can deliver small inhibitory RNA to target tissues in vivo. The efficacy of cardiac RNA interference using a mi...

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Detalles Bibliográficos
Autores principales: Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Klein, Edwin C., Villanueva, Flordeliza S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966949/
https://www.ncbi.nlm.nih.gov/pubmed/27471848
http://dx.doi.org/10.1371/journal.pone.0159751

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