Cargando…
Cardiac Gene Expression Knockdown Using Small Inhibitory RNA-Loaded Microbubbles and Ultrasound
RNA interference has potential therapeutic value for cardiac disease, but targeted delivery of interfering RNA is a challenge. Custom designed microbubbles, in conjunction with ultrasound, can deliver small inhibitory RNA to target tissues in vivo. The efficacy of cardiac RNA interference using a mi...
Autores principales: | Kopechek, Jonathan A., Carson, Andrew R., McTiernan, Charles F., Chen, Xucai, Klein, Edwin C., Villanueva, Flordeliza S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966949/ https://www.ncbi.nlm.nih.gov/pubmed/27471848 http://dx.doi.org/10.1371/journal.pone.0159751 |
Ejemplares similares
-
Ultrasound and Microbubble-targeted Delivery of a microRNA Inhibitor to the Heart Suppresses Cardiac Hypertrophy and Preserves Cardiac Function
por: Kopechek, Jonathan A., et al.
Publicado: (2019) -
Ultrasound Targeted Microbubble Destruction-Mediated Delivery of a Transcription Factor Decoy Inhibits STAT3 Signaling and Tumor Growth
por: Kopechek, Jonathan A., et al.
Publicado: (2015) -
STAT3 decoy oligonucleotide-carrying microbubbles with pulsed ultrasound for enhanced therapeutic effect in head and neck tumors
por: Ramasamy, Thiruganesh, et al.
Publicado: (2020) -
Focal areas of increased lipid concentration on the coating of microbubbles during short tone-burst ultrasound insonification
por: Kooiman, Klazina, et al.
Publicado: (2017) -
Ultrasound with microbubbles
por: Harvey, Chris
Publicado: (2015)