A Novel Strategy for TNF-Alpha Production by 2-APB Induced Downregulated SOCE and Upregulated HSP70 in O. tsutsugamushi-Infected Human Macrophages

Orientia (O.) tsutsugamushi-induced scrub typhus is endemic across many regions of Asia and the Western Pacific, where an estimated 1 million cases occur each year; the majority of patients infected with O. tsutsugamushi end up with a cytokine storm from a severe inflammatory response. Previous repo...

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Detalles Bibliográficos
Autores principales: Wu, Ching-Ying, Hsu, Wen-Li, Wang, Chun-Hsiung, Liang, Jui-Lin, Tsai, Ming-Hsien, Yen, Chia-Jung, Li, Hsiu-Wen, Chiu, Siou-Jin, Chang, Chung-Hsing, Huang, Yaw-Bin, Lin, Ming-Wei, Yoshioka, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966960/
https://www.ncbi.nlm.nih.gov/pubmed/27472555
http://dx.doi.org/10.1371/journal.pone.0159299

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