Cargando…

Profilin connects actin assembly with microtubule dynamics

Profilin controls actin nucleation and assembly processes in eukaryotic cells. Actin nucleation and elongation promoting factors (NEPFs) such as Ena/VASP, formins, and WASP-family proteins recruit profilin:actin for filament formation. Some of these are found to be microtubule associated, making act...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nejedla, Michaela, Sadi, Sara, Sulimenko, Vadym, de Almeida, Francisca Nunes, Blom, Hans, Draber, Pavel, Aspenström, Pontus, Karlsson, Roger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4966980/ https://www.ncbi.nlm.nih.gov/pubmed/27307590 http://dx.doi.org/10.1091/mbc.E15-11-0799

Ejemplares similares

The actin regulator profilin 1 is functionally associated with the mammalian centrosome
por: Nejedlá, Michaela, et al.
Publicado: (2020)

γ-Tubulin in microtubule nucleation and beyond
por: Sulimenko, Vadym, et al.
Publicado: (2022)

Mast Cell Activation and Microtubule Organization Are Modulated by Miltefosine Through Protein Kinase C Inhibition
por: Rubíková, Zuzana, et al.
Publicado: (2018)

Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells
por: Blume, Yaroslav, et al.
Publicado: (2010)

γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis
por: Vinopal, Stanislav, et al.
Publicado: (2012)

Correction: γ-Tubulin 2 Nucleates Microtubules and Is Downregulated in Mouse Early Embryogenesis
por: Vinopal, Stanislav, et al.
Publicado: (2012)

Regulation of Microtubule Nucleation in Mouse Bone Marrow-Derived Mast Cells by Protein Tyrosine Phosphatase SHP-1
por: Klebanovych, Anastasiya, et al.
Publicado: (2019)

Cytoskeleton in Mast Cell Signaling
por: Dráber, Pavel, et al.
Publicado: (2012)

C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress
por: Klebanovych, Anastasiya, et al.
Publicado: (2022)

RhoD regulates cytoskeletal dynamics via the actin nucleation–promoting factor WASp homologue associated with actin Golgi membranes and microtubules
por: Gad, Annica K. B., et al.
Publicado: (2012)

Profilin2 regulates actin rod assembly in neuronal cells
por: Walter, Lisa Marie, et al.
Publicado: (2021)

A structural model of the profilin–formin pacemaker system for actin filament elongation
por: Schutt, Clarence E., et al.
Publicado: (2022)

Biochemical characterization of actin assembly mechanisms with ALS-associated profilin variants
por: Liu, Xinbei, et al.
Publicado: (2022)

Author Correction: A structural model of the profilin–formin pacemaker system for actin filament elongation
por: Schutt, Clarence E., et al.
Publicado: (2023)

The Intrinsic GDP/GTP Exchange Activities of Cdc42 and Rac1 Are Critical Determinants for Their Specific Effects on Mobilization of the Actin Filament System
por: Aspenström, Pontus
Publicado: (2019)

Acanthamoeba actin and profilin can be cross-linked between glutamic acid 364 of actin and lysine 115 of profilin
Publicado: (1989)

Profilin and Mical combine to impair F-actin assembly and promote disassembly and remodeling
por: Grintsevich, Elena E., et al.
Publicado: (2021)

Mechanism of the interaction of human platelet profilin with actin
Publicado: (1991)

Mechanism of regulation of actin polymerization by Physarum profilin
Publicado: (1984)

Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin
Publicado: (1983)

Fission yeast profilin is tailored to facilitate actin assembly by the cytokinesis formin Cdc12
por: Bestul, Andrew J., et al.
Publicado: (2015)

In Vivo Importance of Actin Nucleotide Exchange Catalyzed by Profilin
por: Wolven, Amy K., et al.
Publicado: (2000)

Chlamydomonas reinhardtii formin FOR1 and profilin PRF1 are optimized for acute rapid actin filament assembly
por: Christensen, Jenna R., et al.
Publicado: (2019)

Effects of profilin and profilactin on actin structure and function in living cells
Publicado: (1992)

Reversible binding of actin to gelsolin and profilin in human platelet extracts
Publicado: (1987)

Profilin Enhances Cdc42-Induced Nucleation of Actin Polymerization
por: Yang, Changsong, et al.
Publicado: (2000)

The actin binding protein profilin 1 is critical for mitochondria function
por: Read, Tracy-Ann, et al.
Publicado: (2023)

Dysregulation of Microtubule Nucleating Proteins in Cancer Cells
por: Dráber, Pavel, et al.
Publicado: (2021)

Fluorescent actin analogs with a high affinity for profilin in vitro exhibit an enhanced gradient of assembly in living cells
Publicado: (1994)

Unique Properties of Eukaryote-Type Actin and Profilin Horizontally Transferred to Cyanobacteria
por: Guljamow, Arthur, et al.
Publicado: (2012)

Profilin as a regulator of the membrane-actin cytoskeleton interface in plant cells
por: Sun, Tiantian, et al.
Publicado: (2013)

A unique profilin-actin interface is important for malaria parasite motility
por: Moreau, Catherine A., et al.
Publicado: (2017)

Heimdallarchaea encodes profilin with eukaryotic-like actin regulation and polyproline binding
por: Survery, Sabeen, et al.
Publicado: (2021)

The actin released from profilin--actin complexes is insufficient to account for the increase in F-actin in chemoattractant-stimulated polymorphonuclear leukocytes
Publicado: (1990)

STIP1/HOP Regulates the Actin Cytoskeleton through Interactions with Actin and Changes in Actin-Binding Proteins Cofilin and Profilin
por: Beckley, Samantha Joy, et al.
Publicado: (2020)

Splicing Defects of the Profilin Gene Alter Actin Dynamics in an S. pombe SMN Mutant
por: Antoine, Marie, et al.
Publicado: (2019)

Profilin and formin constitute a pacemaker system for robust actin filament growth
por: Funk, Johanna, et al.
Publicado: (2019)

Evolution of Functional Diversity Among Actin-Binding Profilin Genes in Land Plants
por: Pandey, Dhananjay K., et al.
Publicado: (2020)

Actin-microtubule interplay coordinates spindle assembly in human oocytes
por: Roeles, Johannes, et al.
Publicado: (2019)

Inhibition of polar actin assembly by astral microtubules is required for cytokinesis
por: Chen, Anan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4uu91rm9dp4vei0jjqoldho3ko