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Effects of rAAV-mediated FGF-2 gene transfer and overexpression upon the chondrogenic differentiation processes in human bone marrow aspirates
BACKGROUND: Application of genetically modified bone marrow concentrates in articular cartilage lesions is a promising approach to enhance cartilage repair by stimulating the chondrogenic differentiation processes in sites of injury. METHOD: In the present study, we examined the potential benefits o...
Autores principales: | Frisch, Janina, Venkatesan, Jagadeesh K., Rey-Rico, Ana, Zawada, Adam M., Schmitt, Gertrud, Madry, Henning, Cucchiarini, Magali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967065/ https://www.ncbi.nlm.nih.gov/pubmed/27473203 http://dx.doi.org/10.1186/s40634-016-0052-6 |
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