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The Vitamin E Analog Gamma-Tocotrienol (GT3) Suppresses Radiation-Induced Cytogenetic Damage
PURPOSE: Ionizing radiation (IR) generates reactive oxygen species (ROS), which cause DNA double-strand breaks (DSBs) that are responsible for cytogenetic alterations. Because antioxidants are potent ROS scavengers, we determined whether the vitamin E isoform γ-tocotrienol (GT3), a radio-protective...
Autores principales: | Pathak, Rupak, Bachri, Abdel, Ghosh, Sanchita P., Koturbash, Igor, Boerma, Marjan, Binz, Regina K., Sawyer, Jeffrey R., Hauer-Jensen, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967083/ https://www.ncbi.nlm.nih.gov/pubmed/27216753 http://dx.doi.org/10.1007/s11095-016-1950-0 |
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