Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice

A feature in patients with constitutional DNA-mismatch repair deficiency is agenesis of the corpus callosum, the cause of which has not been established. Here we report a previously unrecognized consequence of deficiency in MSH2, a protein known primarily for its function in correcting nucleotide mi...

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Detalles Bibliográficos
Autores principales: Diouf, Barthelemy, Devaraju, Prakash, Janke, Laura J., Fan, Yiping, Frase, Sharon, Eddins, Donnie, Peters, Jennifer L., Kim, Jieun, Pei, Deqing, Cheng, Cheng, Zakharenko, Stanislav S., Evans, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967871/
https://www.ncbi.nlm.nih.gov/pubmed/27476972
http://dx.doi.org/10.1038/srep30757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967871/
https://www.ncbi.nlm.nih.gov/pubmed/27476972
http://dx.doi.org/10.1038/srep30757

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