Transferrin Receptor 2 Dependent Alterations of Brain Iron Metabolism Affect Anxiety Circuits in the Mouse

The Transferrin Receptor 2 (Tfr2) modulates systemic iron metabolism through the regulation of iron regulator Hepcidin (Hepc) and Tfr2 inactivation causes systemic iron overload. Based on data demonstrating Tfr2 expression in brain, we analysed Tfr2-KO mice in order to examine the molecular, histolo...

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Detalles Bibliográficos
Autores principales: Pellegrino, Rosa Maria, Boda, Enrica, Montarolo, Francesca, Boero, Martina, Mezzanotte, Mariarosa, Saglio, Giuseppe, Buffo, Annalisa, Roetto, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967901/
https://www.ncbi.nlm.nih.gov/pubmed/27477597
http://dx.doi.org/10.1038/srep30725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967901/
https://www.ncbi.nlm.nih.gov/pubmed/27477597
http://dx.doi.org/10.1038/srep30725

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