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Transferrin Receptor 2 Dependent Alterations of Brain Iron Metabolism Affect Anxiety Circuits in the Mouse

The Transferrin Receptor 2 (Tfr2) modulates systemic iron metabolism through the regulation of iron regulator Hepcidin (Hepc) and Tfr2 inactivation causes systemic iron overload. Based on data demonstrating Tfr2 expression in brain, we analysed Tfr2-KO mice in order to examine the molecular, histolo...

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Detalles Bibliográficos
Autores principales:	Pellegrino, Rosa Maria, Boda, Enrica, Montarolo, Francesca, Boero, Martina, Mezzanotte, Mariarosa, Saglio, Giuseppe, Buffo, Annalisa, Roetto, Antonella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967901/ https://www.ncbi.nlm.nih.gov/pubmed/27477597 http://dx.doi.org/10.1038/srep30725

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