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The number of α-synuclein proteins per vesicle gives insights into its physiological function

Although it is well established that the protein α-synuclein (αS) plays an important role in Parkinson’s disease, its physiological function remains largely unknown. It has been reported to bind membranes and to play a role in membrane remodeling processes. The mechanism by which αS remodels membran...

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Detalles Bibliográficos
Autores principales: Fakhree, Mohammad A. A., Zijlstra, Niels, Raiss, Christian C., Siero, Carolus J., Grabmayr, Heinrich, Bausch, Andreas R., Blum, Christian, Claessens, Mireille M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967914/
https://www.ncbi.nlm.nih.gov/pubmed/27477055
http://dx.doi.org/10.1038/srep30658