Towards the development of an enzyme replacement therapy for the metabolic disorder propionic acidemia

Propionic acidemia (PA) is a life-threatening disease caused by the deficiency of a mitochondrial biotin-dependent enzyme known as propionyl coenzyme-A carboxylase (PCC). This enzyme is responsible for degrading the metabolic intermediate, propionyl coenzyme-A (PP-CoA), derived from multiple metabol...

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Detalles Bibliográficos
Autores principales: Darvish-Damavandi, Mahnaz, Ho, Han Kiat, Kang, Tse Siang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968140/
https://www.ncbi.nlm.nih.gov/pubmed/27504265
http://dx.doi.org/10.1016/j.ymgmr.2016.06.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968140/
https://www.ncbi.nlm.nih.gov/pubmed/27504265
http://dx.doi.org/10.1016/j.ymgmr.2016.06.009

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