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Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy

Cases of synchronous prostate and colorectal adenocarcinomas have been sporadically reported. There are case reports on patients with synchronous prostate and rectal cancers treated with external beam radiotherapy alone or combined with high‐dose rate brachytherapy boost to the prostate. Here, we il...

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Autores principales: Ng, Sweet Ping, Tran, Thu, Moloney, Philip, Sale, Charlotte, Mathlum, Maitham, Ong, Grace, Lynch, Rod
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968563/
https://www.ncbi.nlm.nih.gov/pubmed/27512575
http://dx.doi.org/10.1002/jmrs.143
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author Ng, Sweet Ping
Tran, Thu
Moloney, Philip
Sale, Charlotte
Mathlum, Maitham
Ong, Grace
Lynch, Rod
author_facet Ng, Sweet Ping
Tran, Thu
Moloney, Philip
Sale, Charlotte
Mathlum, Maitham
Ong, Grace
Lynch, Rod
author_sort Ng, Sweet Ping
collection PubMed
description Cases of synchronous prostate and colorectal adenocarcinomas have been sporadically reported. There are case reports on patients with synchronous prostate and rectal cancers treated with external beam radiotherapy alone or combined with high‐dose rate brachytherapy boost to the prostate. Here, we illustrate a patient with synchronous prostate and rectal cancers treated using the volumetric arc therapy (VMAT) technique. The patient was treated with radical radiotherapy to 50.4 Gy in 28 fractions to the pelvis, incorporating the involved internal iliac node and the prostate. A boost of 24 Gy in 12 fractions was delivered to the prostate only, using VMAT. Treatment‐related toxicities and follow‐up prostate‐specific antigen and carcinoembryonic antigen were collected for data analysis. At 12 months, the patient achieved complete response for both rectal and prostate cancers without significant treatment‐related toxicities.
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spelling pubmed-49685632016-08-10 Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy Ng, Sweet Ping Tran, Thu Moloney, Philip Sale, Charlotte Mathlum, Maitham Ong, Grace Lynch, Rod J Med Radiat Sci Case Study Cases of synchronous prostate and colorectal adenocarcinomas have been sporadically reported. There are case reports on patients with synchronous prostate and rectal cancers treated with external beam radiotherapy alone or combined with high‐dose rate brachytherapy boost to the prostate. Here, we illustrate a patient with synchronous prostate and rectal cancers treated using the volumetric arc therapy (VMAT) technique. The patient was treated with radical radiotherapy to 50.4 Gy in 28 fractions to the pelvis, incorporating the involved internal iliac node and the prostate. A boost of 24 Gy in 12 fractions was delivered to the prostate only, using VMAT. Treatment‐related toxicities and follow‐up prostate‐specific antigen and carcinoembryonic antigen were collected for data analysis. At 12 months, the patient achieved complete response for both rectal and prostate cancers without significant treatment‐related toxicities. John Wiley and Sons Inc. 2015-10-10 2015-12 /pmc/articles/PMC4968563/ /pubmed/27512575 http://dx.doi.org/10.1002/jmrs.143 Text en © 2015 The Authors. Journal of Medical Radiation Sciences published by Wiley Publishing Asia Pty Ltd on behalf of Australian Institute of Radiography and New Zealand Institute of Medical Radiation Technology. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Study
Ng, Sweet Ping
Tran, Thu
Moloney, Philip
Sale, Charlotte
Mathlum, Maitham
Ong, Grace
Lynch, Rod
Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title_full Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title_fullStr Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title_full_unstemmed Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title_short Synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
title_sort synchronous prostate and rectal adenocarcinomas irradiation utilising volumetric modulated arc therapy
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968563/
https://www.ncbi.nlm.nih.gov/pubmed/27512575
http://dx.doi.org/10.1002/jmrs.143
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