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Proteomic analysis of imatinib-resistant CML-T1 cells reveals calcium homeostasis as a potential therapeutic target

Chronic myeloid leukemia (CML) therapy has markedly improved patient prognosis after introduction of imatinib mesylate for clinical use. However, a subset of patients develops resistance to imatinib and other tyrosine kinase inhibitors (TKIs), mainly due to point mutations in the region encoding the...

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Detalles Bibliográficos
Autores principales:	Toman, O., Kabickova, T., Vit, O., Fiser, R., Polakova, K. Machova, Zach, J., Linhartova, J., Vyoral, D., Petrak, J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968618/ https://www.ncbi.nlm.nih.gov/pubmed/27430982 http://dx.doi.org/10.3892/or.2016.4945

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