Translational and clinical perspectives on sphincter of Oddi dysfunction

Sphincter of Oddi dysfunction is a complex pathophysiologic entity that is associated with significant morbidity causing abdominal pain, nausea, and vomiting. The purpose of this review is to describe the anatomy and physiology of the sphincter of Oddi, to understand the pathologic mechanisms though...

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Autores principales: Kyanam Kabir Baig, Kondal Rao, Wilcox, Charles Melbern
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968664/
https://www.ncbi.nlm.nih.gov/pubmed/27555792
http://dx.doi.org/10.2147/CEG.S84018
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author Kyanam Kabir Baig, Kondal Rao
Wilcox, Charles Melbern
author_facet Kyanam Kabir Baig, Kondal Rao
Wilcox, Charles Melbern
author_sort Kyanam Kabir Baig, Kondal Rao
collection PubMed
description Sphincter of Oddi dysfunction is a complex pathophysiologic entity that is associated with significant morbidity causing abdominal pain, nausea, and vomiting. The purpose of this review is to describe the anatomy and physiology of the sphincter of Oddi, to understand the pathologic mechanisms thought to be responsible for symptomatology, review recent major studies, explore endoscopic and pharmacologic therapies and their efficacy, and to explore future research avenues.
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spelling pubmed-49686642016-08-23 Translational and clinical perspectives on sphincter of Oddi dysfunction Kyanam Kabir Baig, Kondal Rao Wilcox, Charles Melbern Clin Exp Gastroenterol Review Sphincter of Oddi dysfunction is a complex pathophysiologic entity that is associated with significant morbidity causing abdominal pain, nausea, and vomiting. The purpose of this review is to describe the anatomy and physiology of the sphincter of Oddi, to understand the pathologic mechanisms thought to be responsible for symptomatology, review recent major studies, explore endoscopic and pharmacologic therapies and their efficacy, and to explore future research avenues. Dove Medical Press 2016-07-28 /pmc/articles/PMC4968664/ /pubmed/27555792 http://dx.doi.org/10.2147/CEG.S84018 Text en © 2016 Kyanam Kabir Baig and Wilcox. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Review
Kyanam Kabir Baig, Kondal Rao
Wilcox, Charles Melbern
Translational and clinical perspectives on sphincter of Oddi dysfunction
title Translational and clinical perspectives on sphincter of Oddi dysfunction
title_full Translational and clinical perspectives on sphincter of Oddi dysfunction
title_fullStr Translational and clinical perspectives on sphincter of Oddi dysfunction
title_full_unstemmed Translational and clinical perspectives on sphincter of Oddi dysfunction
title_short Translational and clinical perspectives on sphincter of Oddi dysfunction
title_sort translational and clinical perspectives on sphincter of oddi dysfunction
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968664/
https://www.ncbi.nlm.nih.gov/pubmed/27555792
http://dx.doi.org/10.2147/CEG.S84018
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