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Nrf2 expression is increased in peripheral blood mononuclear cells derived from mild–moderate ex-smoker COPD patients with persistent oxidative stress
Inadequacy of antioxidant nuclear factor-E2-related factor 2 (Nrf2) and endoplasmic reticulum stress-mediated unfolded protein response has been implicated in severe chronic obstructive pulmonary disease (COPD) and cigarette smoking-induced emphysema. As evidence suggests that the ability to upregul...
Autores principales: | Fratta Pasini, Anna Maria, Ferrari, Marcello, Stranieri, Chiara, Vallerio, Paola, Mozzini, Chiara, Garbin, Ulisse, Zambon, Giorgia, Cominacini, Luciano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968670/ https://www.ncbi.nlm.nih.gov/pubmed/27555763 http://dx.doi.org/10.2147/COPD.S102218 |
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