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Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
Agriculture workers have increased rates of airway and skeletal disease. Inhalant exposure to agricultural organic dust extract (ODE) induces bone deterioration in mice; yet, mechanisms underlying lung-bone crosstalk remain unclear. Because Toll-like receptor 2 (TLR2) and TLR4 are important in media...
Autores principales: | Staab, Elizabeth, Thiele, Geoffrey M., Clarey, Dillon, Wyatt, Todd A., Romberger, Debra J., Wells, Adam D., Dusad, Anand, Wang, Dong, Klassen, Lynell W., Mikuls, Ted R., Duryee, Michael J., Poole, Jill A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968800/ https://www.ncbi.nlm.nih.gov/pubmed/27479208 http://dx.doi.org/10.1371/journal.pone.0158735 |
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