Generation and Characterization of an IgG4 Monomeric Fc Platform

The immunoglobulin Fc region is a homodimer consisted of two sets of CH2 and CH3 domains and has been exploited to generate two-arm protein fusions with high expression yields, simplified purification processes and extended serum half-life. However, attempts to generate one-arm fusion proteins with...

Descripción completa

Detalles Bibliográficos
Autores principales: Shan, Lu, Colazet, Magali, Rosenthal, Kim L., Yu, Xiang-Qing, Bee, Jared S., Ferguson, Andrew, Damschroder, Melissa M., Wu, Herren, Dall’Acqua, William F., Tsui, Ping, Oganesyan, Vaheh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968834/
https://www.ncbi.nlm.nih.gov/pubmed/27479095
http://dx.doi.org/10.1371/journal.pone.0160345

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4968834/
https://www.ncbi.nlm.nih.gov/pubmed/27479095
http://dx.doi.org/10.1371/journal.pone.0160345

Ejemplares similares