Subretinal mononuclear phagocytes induce cone segment loss via IL-1β

Photo-transduction in cone segments (CS) is crucial for high acuity daytime vision. For ill-defined reasons, CS degenerate in retinitis pigmentosa (RP) and in the transitional zone (TZ) of atrophic zones (AZ), which characterize geographic atrophy (GA). Our experiments confirm the loss of cone segme...

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Detalles Bibliográficos
Autores principales: Eandi, Chiara M, Charles Messance, Hugo, Augustin, Sébastien, Dominguez, Elisa, Lavalette, Sophie, Forster, Valérie, Hu, Shulong Justin, Siquieros, Lourdes, Craft, Cheryl Mae, Sahel, José-Alain, Tadayoni, Ramin, Paques, Michel, Guillonneau, Xavier, Sennlaub, Florian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Human Biology and Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969036/
https://www.ncbi.nlm.nih.gov/pubmed/27438413
http://dx.doi.org/10.7554/eLife.16490

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