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Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review

Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cra...

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Autores principales: Galgano, Michael A, Padalino, David J, Fullmer, Joseph, Krishnamurthy, Satish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969148/
https://www.ncbi.nlm.nih.gov/pubmed/27493842
http://dx.doi.org/10.7759/cureus.510
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author Galgano, Michael A
Padalino, David J
Fullmer, Joseph
Krishnamurthy, Satish
author_facet Galgano, Michael A
Padalino, David J
Fullmer, Joseph
Krishnamurthy, Satish
author_sort Galgano, Michael A
collection PubMed
description Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation.
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spelling pubmed-49691482016-08-04 Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review Galgano, Michael A Padalino, David J Fullmer, Joseph Krishnamurthy, Satish Cureus Oncology Pilocytic astrocytomas are histologically benign tumors, generally found in the pediatric population. Onset of symptoms is generally insidious, predominantly stemming from mass effect upon nearby structures. Patients harboring a pilocytic astrocytoma may present with gait disturbance, headaches, cranial nerve deficits, as well as hydrocephalus, depending on the exact location. Although cases of adult pilocytic astrocytomas in the adult population are described, they are quite uncommon. We present a case of an adult female presenting with acute neurological compromise resulting from an acutely hemorrhagic posterior fossa pilocytic astrocytoma. Her initial neurological assessment was consistent with a Glasgow coma scale of 4T, as the patient was experiencing decerebrate posturing. An emergent external ventricular drain was placed in the emergency department for acute hydrocephalus as a temporizing measure, prior to evacuation of the associated subdural and intratumoral hemorrhages, as well as resection of the mass. After a long hospital course and extensive rehabilitation, the patient made a remarkable recovery and eventually gave birth to a child via Caesarean section three years after her initial presentation. Cureus 2016-02-24 /pmc/articles/PMC4969148/ /pubmed/27493842 http://dx.doi.org/10.7759/cureus.510 Text en Copyright © 2016, Galgano et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Oncology
Galgano, Michael A
Padalino, David J
Fullmer, Joseph
Krishnamurthy, Satish
Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title_full Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title_fullStr Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title_full_unstemmed Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title_short Hemorrhagic Pilocytic Astrocytomas in Adults: A Case Report and Literature Review
title_sort hemorrhagic pilocytic astrocytomas in adults: a case report and literature review
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969148/
https://www.ncbi.nlm.nih.gov/pubmed/27493842
http://dx.doi.org/10.7759/cureus.510
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