Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration

In this data article, carboxyfluorescein-loaded liposomes were prepared and purified from free carboxyfluorescein using gel filtration chromatography in the first part. In the next part, following preparation of anti-VEGF siRNA loaded liposomes incorporating hydrophobically modified G2 PAMAM dendrim...

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Detalles Bibliográficos
Autores principales: Golkar, Nasim, Samani, Soliman Mohammadi, Tamaddon, Ali Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969245/
https://www.ncbi.nlm.nih.gov/pubmed/27508257
http://dx.doi.org/10.1016/j.dib.2016.06.064
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author Golkar, Nasim
Samani, Soliman Mohammadi
Tamaddon, Ali Mohammad
author_facet Golkar, Nasim
Samani, Soliman Mohammadi
Tamaddon, Ali Mohammad
author_sort Golkar, Nasim
collection PubMed
description In this data article, carboxyfluorescein-loaded liposomes were prepared and purified from free carboxyfluorescein using gel filtration chromatography in the first part. In the next part, following preparation of anti-VEGF siRNA loaded liposomes incorporating hydrophobically modified G2 PAMAM dendrimer (G2-Chol(40%)) (Golkar et al., 2016) [1], the cell growth inhibition induced by the formulations (siRNA/Metafectene complexes and siRNA loaded liposomes incorporating hydrophobic G2) was evaluated at two exposure times through MTT assay in a breast cancer cell (SKBR-3) and compared by two-way ANOVA.
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spelling pubmed-49692452016-08-09 Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration Golkar, Nasim Samani, Soliman Mohammadi Tamaddon, Ali Mohammad Data Brief Data Article In this data article, carboxyfluorescein-loaded liposomes were prepared and purified from free carboxyfluorescein using gel filtration chromatography in the first part. In the next part, following preparation of anti-VEGF siRNA loaded liposomes incorporating hydrophobically modified G2 PAMAM dendrimer (G2-Chol(40%)) (Golkar et al., 2016) [1], the cell growth inhibition induced by the formulations (siRNA/Metafectene complexes and siRNA loaded liposomes incorporating hydrophobic G2) was evaluated at two exposure times through MTT assay in a breast cancer cell (SKBR-3) and compared by two-way ANOVA. Elsevier 2016-07-06 /pmc/articles/PMC4969245/ /pubmed/27508257 http://dx.doi.org/10.1016/j.dib.2016.06.064 Text en © 2016 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Data Article
Golkar, Nasim
Samani, Soliman Mohammadi
Tamaddon, Ali Mohammad
Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title_full Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title_fullStr Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title_full_unstemmed Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title_short Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration
title_sort data on cell growth inhibition induced by anti-vegf sirna delivered by stealth liposomes incorporating g2 pamam-cholesterol versus metafectene® as a function of exposure time and sirna concentration
topic Data Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969245/
https://www.ncbi.nlm.nih.gov/pubmed/27508257
http://dx.doi.org/10.1016/j.dib.2016.06.064
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