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Redundant roles of the phosphatidate phosphatase family in triacylglycerol synthesis in human adipocytes

AIMS/HYPOTHESIS: In mammals, the evolutionary conserved family of Mg(2+)-dependent phosphatidate phosphatases (PAP1), involved in phospholipid and triacylglycerol synthesis, consists of lipin-1, lipin-2 and lipin-3. While mutations in the murine Lpin1 gene cause lipodystrophy and its knockdown in mo...

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Detalles Bibliográficos
Autores principales:	Temprano, Ana, Sembongi, Hiroshi, Han, Gil-Soo, Sebastián, David, Capellades, Jordi, Moreno, Cristóbal, Guardiola, Juan, Wabitsch, Martin, Richart, Cristóbal, Yanes, Oscar, Zorzano, Antonio, Carman, George M., Siniossoglou, Symeon, Miranda, Merce
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969345/ https://www.ncbi.nlm.nih.gov/pubmed/27344312 http://dx.doi.org/10.1007/s00125-016-4018-0

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