Cell type-specific deletion in mice reveals roles for PAS kinase in insulin and glucagon production

AIMS/HYPOTHESIS: Per-Arnt-Sim kinase (PASK) is a nutrient-regulated domain-containing protein kinase previously implicated in the control of insulin gene expression and glucagon secretion. Here, we explore the roles of PASK in the control of islet hormone release, by generating mice with selective d...

Descripción completa

Detalles Bibliográficos
Autores principales: Semplici, Francesca, Mondragon, Angeles, Macintyre, Benedict, Madeyski-Bengston, Katja, Persson-Kry, Anette, Barr, Sara, Ramne, Anna, Marley, Anna, McGinty, James, French, Paul, Soedling, Helen, Yokosuka, Ryohsuke, Gaitan, Julien, Lang, Jochen, Migrenne-Li, Stephanie, Philippe, Erwann, Herrera, Pedro L., Magnan, Christophe, da Silva Xavier, Gabriela, Rutter, Guy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969360/
https://www.ncbi.nlm.nih.gov/pubmed/27338626
http://dx.doi.org/10.1007/s00125-016-4025-1

Ejemplares similares

Ejemplares similares