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Thyroid abnormalities in paediatric patients with vitiligo: retrospective study

INTRODUCTION: The association between vitiligo and thyroid disease is not fully investigated especially in paediatric patients. AIM: To determine the incidence of vitiligo and thyroid disorders in children. This is the first report from middle Anatolia and the second report from Turkey. MATERIAL AND...

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Autores principales: Kartal, Demet, Borlu, Murat, Çınar, Salih Levent, Kesikoğlu, Ayten, Utaş, Serap
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969420/
https://www.ncbi.nlm.nih.gov/pubmed/27512360
http://dx.doi.org/10.5114/ada.2016.60617
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author Kartal, Demet
Borlu, Murat
Çınar, Salih Levent
Kesikoğlu, Ayten
Utaş, Serap
author_facet Kartal, Demet
Borlu, Murat
Çınar, Salih Levent
Kesikoğlu, Ayten
Utaş, Serap
author_sort Kartal, Demet
collection PubMed
description INTRODUCTION: The association between vitiligo and thyroid disease is not fully investigated especially in paediatric patients. AIM: To determine the incidence of vitiligo and thyroid disorders in children. This is the first report from middle Anatolia and the second report from Turkey. MATERIAL AND METHODS: A retrospective chart review was performed to examine the presence of thyroid abnormalities in paediatric patients who had been admitted to the dermatology department with vitiligo. RESULTS: A total of 155 paediatric patients, including 80 (52%) male and 75 (48%) female patients were included. The mean age was 8.6 years. Non segmental vitiligo was the most common type of the disease in 140 (90%) reviewed patients, while segmental vitiligo appeared only in 15 (10%) patients. The mean onset of vitiligo was 5.6 ±0.9 years. A family history of vitiligo was found in 14 (9%) children. Thirty-four (22%) patients had thyroid function tests and/or thyroid autoantibody abnormality. All of these patients had non segmental vitiligo. It was statistically significant (p < 0.05) in types of vitiligo and thyroid disease parameters. CONCLUSIONS: Our results show that it may be useful to screen thyroid in children with non segmental vitiligo.
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spelling pubmed-49694202016-08-10 Thyroid abnormalities in paediatric patients with vitiligo: retrospective study Kartal, Demet Borlu, Murat Çınar, Salih Levent Kesikoğlu, Ayten Utaş, Serap Postepy Dermatol Alergol Original Paper INTRODUCTION: The association between vitiligo and thyroid disease is not fully investigated especially in paediatric patients. AIM: To determine the incidence of vitiligo and thyroid disorders in children. This is the first report from middle Anatolia and the second report from Turkey. MATERIAL AND METHODS: A retrospective chart review was performed to examine the presence of thyroid abnormalities in paediatric patients who had been admitted to the dermatology department with vitiligo. RESULTS: A total of 155 paediatric patients, including 80 (52%) male and 75 (48%) female patients were included. The mean age was 8.6 years. Non segmental vitiligo was the most common type of the disease in 140 (90%) reviewed patients, while segmental vitiligo appeared only in 15 (10%) patients. The mean onset of vitiligo was 5.6 ±0.9 years. A family history of vitiligo was found in 14 (9%) children. Thirty-four (22%) patients had thyroid function tests and/or thyroid autoantibody abnormality. All of these patients had non segmental vitiligo. It was statistically significant (p < 0.05) in types of vitiligo and thyroid disease parameters. CONCLUSIONS: Our results show that it may be useful to screen thyroid in children with non segmental vitiligo. Termedia Publishing House 2016-06-17 2016-06 /pmc/articles/PMC4969420/ /pubmed/27512360 http://dx.doi.org/10.5114/ada.2016.60617 Text en Copyright © 2016 Termedia Sp. z o.o http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Kartal, Demet
Borlu, Murat
Çınar, Salih Levent
Kesikoğlu, Ayten
Utaş, Serap
Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title_full Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title_fullStr Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title_full_unstemmed Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title_short Thyroid abnormalities in paediatric patients with vitiligo: retrospective study
title_sort thyroid abnormalities in paediatric patients with vitiligo: retrospective study
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969420/
https://www.ncbi.nlm.nih.gov/pubmed/27512360
http://dx.doi.org/10.5114/ada.2016.60617
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