Small Molecular-Sized Artesunate Attenuates Ocular Neovascularization via VEGFR2, PKCα, and PDGFR Targets

Ocular neovascularization (NV) is the primary cause of blindness in many ocular diseases. Large molecular weight anti- vascular endothelial growth factor (VEGF) protein drugs, such as Avastin and Lucentis, have saved the vision of millions. However, approximately 20–30% of patients respond poorly to...

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Detalles Bibliográficos
Autores principales: Zong, Yao, Yuan, Yongguang, Qian, Xiaobing, Huang, Zhen, Yang, Wei, Lin, Leilei, Zheng, Qishan, Li, Yujie, He, Huining, Gao, Qianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969591/
https://www.ncbi.nlm.nih.gov/pubmed/27480521
http://dx.doi.org/10.1038/srep30843

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