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Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease

Celiac disease is triggered by partially digested gluten proteins. Enzyme therapies that complete protein digestion in vivo could support a gluten-free diet, but the barrier to completeness is high. Current options require enzyme amounts on the same order as the protein meal itself. In this study, w...

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Detalles Bibliográficos
Autores principales: Rey, Martial, Yang, Menglin, Lee, Linda, Zhang, Ye, Sheff, Joey G., Sensen, Christoph W., Mrazek, Hynek, Halada, Petr, Man, Petr, McCarville, Justin L, Verdu, Elena F., Schriemer, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969619/
https://www.ncbi.nlm.nih.gov/pubmed/27481162
http://dx.doi.org/10.1038/srep30980

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