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Methylation of the leukocyte glucocorticoid receptor gene promoter in adults: associations with early adversity and depressive, anxiety and substance-use disorders
Early adversity increases risk for developing psychopathology. Epigenetic modification of stress reactivity genes is a likely mechanism contributing to this risk. The glucocorticoid receptor (GR) gene is of particular interest because of the regulatory role of the GR in hypothalamic–pituitary–adrena...
Autores principales: | Tyrka, A R, Parade, S H, Welch, E S, Ridout, K K, Price, L H, Marsit, C, Philip, N S, Carpenter, L L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969762/ https://www.ncbi.nlm.nih.gov/pubmed/27378548 http://dx.doi.org/10.1038/tp.2016.112 |
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