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Effects of dexmedetomidine and esmolol on systemic hemodynamics and exogenous lactate clearance in early experimental septic shock

BACKGROUND: Persistent hyperlactatemia during septic shock is multifactorial. Hypoperfusion-related anaerobic production and adrenergic-driven aerobic generation together with impaired lactate clearance have been implicated. An excessive adrenergic response could contribute to persistent hyperlactat...

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Detalles Bibliográficos
Autores principales: Hernández, Glenn, Tapia, Pablo, Alegría, Leyla, Soto, Dagoberto, Luengo, Cecilia, Gomez, Jussara, Jarufe, Nicolas, Achurra, Pablo, Rebolledo, Rolando, Bruhn, Alejandro, Castro, Ricardo, Kattan, Eduardo, Ospina-Tascón, Gustavo, Bakker, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4969982/
https://www.ncbi.nlm.nih.gov/pubmed/27480413
http://dx.doi.org/10.1186/s13054-016-1419-x