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Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice

Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring p...

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Autores principales: González-Sánchez, Carlos, Fraile, Juan-Carlos, Pérez-Turiel, Javier, Damm, Ellen, Schneider, Jochen G., Zimmermann, Heiko, Schmitt, Daniel, Ihmig, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970099/
https://www.ncbi.nlm.nih.gov/pubmed/27399713
http://dx.doi.org/10.3390/s16071052
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author González-Sánchez, Carlos
Fraile, Juan-Carlos
Pérez-Turiel, Javier
Damm, Ellen
Schneider, Jochen G.
Zimmermann, Heiko
Schmitt, Daniel
Ihmig, Frank R.
author_facet González-Sánchez, Carlos
Fraile, Juan-Carlos
Pérez-Turiel, Javier
Damm, Ellen
Schneider, Jochen G.
Zimmermann, Heiko
Schmitt, Daniel
Ihmig, Frank R.
author_sort González-Sánchez, Carlos
collection PubMed
description Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown.
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spelling pubmed-49700992016-08-04 Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice González-Sánchez, Carlos Fraile, Juan-Carlos Pérez-Turiel, Javier Damm, Ellen Schneider, Jochen G. Zimmermann, Heiko Schmitt, Daniel Ihmig, Frank R. Sensors (Basel) Article Animal testing plays a vital role in biomedical research. Stress reduction is important for improving research results and increasing the welfare and the quality of life of laboratory animals. To estimate stress we believe it is of great importance to develop non-invasive techniques for monitoring physiological signals during the transport of laboratory animals, thereby allowing the gathering of information on the transport conditions, and, eventually, the improvement of these conditions. Here, we study the suitability of commercially available electric potential integrated circuit (EPIC) sensors, using both contact and contactless techniques, for monitoring the heart rate and breathing rate of non-restrained, non-sedated laboratory mice. The design has been tested under different scenarios with the aim of checking the plausibility of performing contactless capture of mouse heart activity (ideally with an electrocardiogram). First experimental results are shown. MDPI 2016-07-07 /pmc/articles/PMC4970099/ /pubmed/27399713 http://dx.doi.org/10.3390/s16071052 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
González-Sánchez, Carlos
Fraile, Juan-Carlos
Pérez-Turiel, Javier
Damm, Ellen
Schneider, Jochen G.
Zimmermann, Heiko
Schmitt, Daniel
Ihmig, Frank R.
Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_full Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_fullStr Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_full_unstemmed Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_short Capacitive Sensing for Non-Invasive Breathing and Heart Monitoring in Non-Restrained, Non-Sedated Laboratory Mice
title_sort capacitive sensing for non-invasive breathing and heart monitoring in non-restrained, non-sedated laboratory mice
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970099/
https://www.ncbi.nlm.nih.gov/pubmed/27399713
http://dx.doi.org/10.3390/s16071052
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