CHEK2 represses breast stromal fibroblasts and their paracrine tumor-promoting effects through suppressing SDF-1 and IL-6

BACKGROUND: Active fibroblasts, the predominant and the most active cells of breast cancer stroma, are responsible for tumor growth and spread. However, the molecular mediators and pathways responsible for stromal fibroblast activation, and their paracrine pro-carcinogenic effects are still not well...

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Detalles Bibliográficos
Autores principales: Al-Rakan, Maha A., Hendrayani, Siti-Faujiah, Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970236/
https://www.ncbi.nlm.nih.gov/pubmed/27484185
http://dx.doi.org/10.1186/s12885-016-2614-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970236/
https://www.ncbi.nlm.nih.gov/pubmed/27484185
http://dx.doi.org/10.1186/s12885-016-2614-5

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