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Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma

A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63‐year‐old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with i...

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Autores principales: Hayakawa, Takamitsu, Tajima, Shogo, Takanashi, Yusuke, Takahashi, Tsuyoshi, Neyatani, Hiroshi, Funai, Kazuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970311/
https://www.ncbi.nlm.nih.gov/pubmed/27516891
http://dx.doi.org/10.1002/rcr2.175
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author Hayakawa, Takamitsu
Tajima, Shogo
Takanashi, Yusuke
Takahashi, Tsuyoshi
Neyatani, Hiroshi
Funai, Kazuhito
author_facet Hayakawa, Takamitsu
Tajima, Shogo
Takanashi, Yusuke
Takahashi, Tsuyoshi
Neyatani, Hiroshi
Funai, Kazuhito
author_sort Hayakawa, Takamitsu
collection PubMed
description A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63‐year‐old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia confirmed the diagnosis of sarcomatoid malignant pleural mesothelioma. The patient underwent left extra‐pleural pneumonectomy. Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar‐filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar‐filling growth pattern, despite having not been thoroughly categorized in the World Health Organization (WHO) classification.
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spelling pubmed-49703112016-08-11 Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma Hayakawa, Takamitsu Tajima, Shogo Takanashi, Yusuke Takahashi, Tsuyoshi Neyatani, Hiroshi Funai, Kazuhito Respirol Case Rep Case Reports A case of sarcomatoid malignant pleural mesothelioma showing extremely rare growth pattern is described. A 63‐year‐old man presented to our hospital with left pleural effusion. A computed tomography (CT) scan of the chest showed diffusely thickened left visceral and parietal pleura associated with intermingled pulmonary infiltrative shadowing. Biopsy of the pleura under general anaesthesia confirmed the diagnosis of sarcomatoid malignant pleural mesothelioma. The patient underwent left extra‐pleural pneumonectomy. Histopathologically, the sarcomatoid spindle tumour cells changed their morphology to polygonal cells in the pulmonary parenchyma and grew upwards, filling the alveolar space without the destruction of its septa, showing an alveolar‐filling growth pattern. The current report indicates a case of sarcomatoid pleural mesothelioma that shows an alveolar‐filling growth pattern, despite having not been thoroughly categorized in the World Health Organization (WHO) classification. John Wiley & Sons, Ltd 2016-07-04 /pmc/articles/PMC4970311/ /pubmed/27516891 http://dx.doi.org/10.1002/rcr2.175 Text en © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Hayakawa, Takamitsu
Tajima, Shogo
Takanashi, Yusuke
Takahashi, Tsuyoshi
Neyatani, Hiroshi
Funai, Kazuhito
Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title_full Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title_fullStr Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title_full_unstemmed Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title_short Alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
title_sort alveolar‐filling growth pattern of sarcomatoid malignant pleural mesothelioma
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970311/
https://www.ncbi.nlm.nih.gov/pubmed/27516891
http://dx.doi.org/10.1002/rcr2.175
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