Cargando…

Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia

Mycobacterium avium complex (MAC) infection is a major medical concern in Japan because of its increased prevalence and associated mortality. A common radiological feature in pulmonary MAC infection is a mixture of two basic patterns: fibrocavitary and nodular bronchiectatic; however, lobar consolid...

Descripción completa

Detalles Bibliográficos
Autores principales: Okuzumi, Shinichi, Minematsu, Naoto, Sasaki, Mamoru, Ohsawa, Kazuma, Murakami, Marohito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970312/
https://www.ncbi.nlm.nih.gov/pubmed/27516892
http://dx.doi.org/10.1002/rcr2.176
_version_ 1782445956621402112
author Okuzumi, Shinichi
Minematsu, Naoto
Sasaki, Mamoru
Ohsawa, Kazuma
Murakami, Marohito
author_facet Okuzumi, Shinichi
Minematsu, Naoto
Sasaki, Mamoru
Ohsawa, Kazuma
Murakami, Marohito
author_sort Okuzumi, Shinichi
collection PubMed
description Mycobacterium avium complex (MAC) infection is a major medical concern in Japan because of its increased prevalence and associated mortality. A common radiological feature in pulmonary MAC infection is a mixture of two basic patterns: fibrocavitary and nodular bronchiectatic; however, lobar consolidation is rare. We report an 83‐year‐old man with lobar caseous pneumonia caused by pulmonary MAC infection. Radiological findings were predominantly composed of dense lobar consolidation and ground‐glass opacity. A diagnosis was made in accordance with the clinical and microbiological criteria set by the American Thoracic Society. A histological examination of lung specimens obtained by using a bronchoscope revealed a caseous granulomatous inflammation with an appearance of Langhans cells. The patient was treated using combined mycobacterium chemotherapy with an initial positive response for 6 months; however, the disease progressed later. We suggest that an awareness of lobar pneumonic consolidation as a rare radiological finding in pulmonary MAC infection is important.
format Online
Article
Text
id pubmed-4970312
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher John Wiley & Sons, Ltd
record_format MEDLINE/PubMed
spelling pubmed-49703122016-08-11 Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia Okuzumi, Shinichi Minematsu, Naoto Sasaki, Mamoru Ohsawa, Kazuma Murakami, Marohito Respirol Case Rep Case Reports Mycobacterium avium complex (MAC) infection is a major medical concern in Japan because of its increased prevalence and associated mortality. A common radiological feature in pulmonary MAC infection is a mixture of two basic patterns: fibrocavitary and nodular bronchiectatic; however, lobar consolidation is rare. We report an 83‐year‐old man with lobar caseous pneumonia caused by pulmonary MAC infection. Radiological findings were predominantly composed of dense lobar consolidation and ground‐glass opacity. A diagnosis was made in accordance with the clinical and microbiological criteria set by the American Thoracic Society. A histological examination of lung specimens obtained by using a bronchoscope revealed a caseous granulomatous inflammation with an appearance of Langhans cells. The patient was treated using combined mycobacterium chemotherapy with an initial positive response for 6 months; however, the disease progressed later. We suggest that an awareness of lobar pneumonic consolidation as a rare radiological finding in pulmonary MAC infection is important. John Wiley & Sons, Ltd 2016-07-05 /pmc/articles/PMC4970312/ /pubmed/27516892 http://dx.doi.org/10.1002/rcr2.176 Text en © 2016 The Authors. Respirology Case Reports published by John Wiley & Sons Australia, Ltd on behalf of The Asian Pacific Society of Respirology This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Okuzumi, Shinichi
Minematsu, Naoto
Sasaki, Mamoru
Ohsawa, Kazuma
Murakami, Marohito
Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title_full Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title_fullStr Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title_full_unstemmed Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title_short Pulmonary Mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
title_sort pulmonary mycobacterium avium infection demonstrating unusual lobar caseous pneumonia
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970312/
https://www.ncbi.nlm.nih.gov/pubmed/27516892
http://dx.doi.org/10.1002/rcr2.176
work_keys_str_mv AT okuzumishinichi pulmonarymycobacteriumaviuminfectiondemonstratingunusuallobarcaseouspneumonia
AT minematsunaoto pulmonarymycobacteriumaviuminfectiondemonstratingunusuallobarcaseouspneumonia
AT sasakimamoru pulmonarymycobacteriumaviuminfectiondemonstratingunusuallobarcaseouspneumonia
AT ohsawakazuma pulmonarymycobacteriumaviuminfectiondemonstratingunusuallobarcaseouspneumonia
AT murakamimarohito pulmonarymycobacteriumaviuminfectiondemonstratingunusuallobarcaseouspneumonia