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mito-QC illuminates mitophagy and mitochondrial architecture in vivo

Autophagic turnover of mitochondria, termed mitophagy, is proposed to be an essential quality-control (QC) mechanism of pathophysiological relevance in mammals. However, if and how mitophagy proceeds within specific cellular subtypes in vivo remains unclear, largely because of a lack of tractable to...

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Detalles Bibliográficos
Autores principales: McWilliams, Thomas G., Prescott, Alan R., Allen, George F.G., Tamjar, Jevgenia, Munson, Michael J., Thomson, Calum, Muqit, Miratul M.K., Ganley, Ian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970326/
https://www.ncbi.nlm.nih.gov/pubmed/27458135
http://dx.doi.org/10.1083/jcb.201603039