Cargando…
Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
Mitochondria are considered autonomous organelles, physically separated from endocytic and biosynthetic pathways. However, recent work uncovered a PINK1/parkin-dependent vesicle transport pathway wherein oxidized or damaged mitochondrial content are selectively delivered to the late endosome/lysosom...
Autores principales: | McLelland, Gian-Luca, Lee, Sydney A., McBride, Heidi M., Fon, Edward A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970327/ https://www.ncbi.nlm.nih.gov/pubmed/27458136 http://dx.doi.org/10.1083/jcb.201603105 |
Ejemplares similares
-
Parkin- and PINK1-Dependent Mitophagy in Neurons: Will the Real Pathway Please Stand Up?
por: Grenier, Karl, et al.
Publicado: (2013) -
A mitochondrial-derived vesicle HOPS to endolysosomes using Syntaxin-17
por: Juhász, Gábor
Publicado: (2016) -
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
por: McLelland, Gian-Luca, et al.
Publicado: (2018) -
Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles
por: Ramirez, Adrian, et al.
Publicado: (2022) -
Parkin mitochondria in the autophagosome
por: McBride, Heidi M.
Publicado: (2008)