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Midbody remnant licenses primary cilia formation in epithelial cells

Tethered midbody remnants dancing across apical microvilli, encountering the centrosome, and beckoning forth a cilium—who would have guessed this is how polarized epithelial cells coordinate the end of mitosis and the beginning of ciliogenesis? New evidence from Bernabé-Rubio et al. (2016. J. Cell B...

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Detalles Bibliográficos
Autor principal: Ott, Carolyn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970334/
https://www.ncbi.nlm.nih.gov/pubmed/27482049
http://dx.doi.org/10.1083/jcb.201607046
Descripción
Sumario:Tethered midbody remnants dancing across apical microvilli, encountering the centrosome, and beckoning forth a cilium—who would have guessed this is how polarized epithelial cells coordinate the end of mitosis and the beginning of ciliogenesis? New evidence from Bernabé-Rubio et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601020) supports this emerging model.