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Oxygen-18 Kinetic Isotope Effects of Nonheme Iron Enzymes HEPD and MPnS Support Iron(III) Superoxide as the Hydrogen Abstraction Species

[Image: see text] Nonheme iron oxygenases that carry out four-electron oxidations of substrate have been proposed to employ iron(III) superoxide species to initiate this reaction [Paria, S.; Que, L.; Paine, T. K. Angew. Chem. Int. Ed.2011, 50, 11129]. Here we report experimental evidence in support...

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Detalles Bibliográficos
Autores principales:	Zhu, Hui, Peck, Spencer C., Bonnot, Florence, van der Donk, Wilfred A., Klinman, Judith P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2015
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4970508/ https://www.ncbi.nlm.nih.gov/pubmed/26267117 http://dx.doi.org/10.1021/jacs.5b03907

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